Something has fundamentally shifted in aesthetic medicine. London patients are no longer asking to look different. They are asking to look better — and they are choosing treatments that make their skin work harder rather than filling it with something foreign. Here is what is driving the change, and what it means for you.

Polynucleotide treatment has become one of the most requested skin quality treatments in the UK and at Skin Lab Medispa in Marylebone, we offer four premium brands: Rejuran, Ameela, Plinest, and Vitaran. This complete guide explains how they work, which brand is right for you, and what to expect from a course of treatment.